Nanoparticles with intermediate hydrophobicity polarize macrophages to plaque-specific Mox phenotype via Nrf2 and HO-1 activation
Shumei Zhai, Xianzhi Zhang, Mingdi Jiang, Yujia Liu, Guangbo Qu, Xiaomiao Cui, Cristina‐Maria Hirschbiegel, Yuanchang Liu, Colby Alves, Yi-Wei Lee, Guibin Jiang, Bing Yan, Vincent M. Rotello
Topics & Concepts
Reactive oxygen speciesMacrophage polarizationChemistryIntracellularCell biologyMOX fuelOxidative phosphorylationMacrophagePhosphorylationDownregulation and upregulationBiophysicsBiochemistryBiologyIn vitroGenePlutoniumRadiochemistryImmune cells in cancerNeuroinflammation and Neurodegeneration MechanismsPhagocytosis and Immune Regulation