Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection
Sarah S. Gabriel, Carlson Tsui, David Chisanga, Flora Weber, Manuela Llano-León, Patrick M. Gubser, Laurent Bartholin, Fernando Souza-Fonseca-Guimarães, Nicholas D. Huntington, Wei Shi, Daniel T. Utzschneider, Axel Kallies
Topics & Concepts
BiologyPI3K/AKT/mTOR pathwayCell biologyCytotoxic T cellT cellCellImmune systemSignal transductionImmunologyBiochemistryIn vitroImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses