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CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1β signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice

Jing Qi, Xueqing Yan, Lanqian Li, Kexin Qiu, Weizhi Huang, Zixiong Zhou

2023International Immunopharmacology20 citationsDOI

Topics & Concepts

CXCL5Hepatic stellate cellTLR4Internal medicineChemistryEndocrinologyChemokineBiologyImmunologyInflammationMedicineLiver Disease Diagnosis and TreatmentLiver physiology and pathologyLiver Disease and Transplantation
CXCL5 promotes lipotoxicity of hepatocytes through upregulating NLRP3/Caspase-1/IL-1β signaling in Kupffer cells and exacerbates nonalcoholic steatohepatitis in mice | Litcius