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Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Elijah Weber, Raju Subramanian, William Rowe, Michael Graupe, John Ling, Gong Shen, Rebecca Begley, Jennifer E. Sager, Scott A. Wolckenhauer, Martin S. Rhee, Ramesh Palaparthy, Renu Singh

2024Clinical Pharmacokinetics17 citationsDOI

Topics & Concepts

PharmacokineticsUrineTolerabilityPharmacologyFecesMetaboliteChemistryMedicineDosingPlaceboCohortInternal medicineAdverse effectBiologyPathologyMicrobiologyAlternative medicineHIV/AIDS drug development and treatmentHIV Research and TreatmentHIV-related health complications and treatments
Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion | Litcius