Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
Lena M. Kranz, Mustafa Diken, Heinrich Haas, Sebastian Kreiter, Carmen Loquai, Kerstin C. Reuter, Martin Meng, Daniel Fritz, Fulvia Vascotto, Hossam Hefesha, Christian Grunwitz, Mathias Vormehr, Yves Hüsemann, Abderraouf Selmi, Andreas N. Kuhn, Janina Buck, Evelyna Derhovanessian, Richard Rae, Sebastian Attig, Jan Diekmann, Robert A. Jabulowsky, Sandra Heesch, Jessica C. Hassel, Peter Langguth, Stephan Grabbe, Christoph Huber, Özlem Türeci, Uğur Şahin
Topics & Concepts
Systemic administrationDendritic cellAntigenCancer immunotherapyImmune systemImmunotherapyImmunologyRNAAntigen-presenting cellBiologyCancer researchMedicineT cellIn vivoGeneBiochemistryBiotechnologyImmunotherapy and Immune ResponsesRNA Interference and Gene DeliveryImmune Response and Inflammation