Pharmacological and toxicological effects of Nicotiana tabacum
Ali Esmail Al‐Snafi
Abstract
Nicotiana tabacum (Family: Solanaceae) was used traditionally for wide range of disorders, it administered externally for bites of poisonous reptiles and insects, pain, neuralgia, gout, to enhance hair growth, in the treatment of ringworm, ulcers, wounds and as respiratory stimulant. The leaves contained sesquiterpene, alkaloids, lignans, flavonoids, phenolic compounds, tannins, steroids, terpenoids, cardiac glycosides, essential oils, saponins, quinines, polypeptides, phenylpropanoids, chromanones, biphenyls and isocoumarins. The previous studied showed that Nicotiana tabacum possessed many pharmacological effects included antioxidant, antimicrobial, antiparasitic, analgesic, antidiabetic, antifertility, anti-aphthous, cytotoxic and neuropharmacological effects. The current review focused on the chemical constituents and pharmacological effects of Nicotiana tabacum.