Precision Oncology: 2024 in Review
Matteo Repetto, Nicole Fernandez, Alexander Drilon, Debyani Chakravarty
Abstract
This article discusses the specific advances made in precision oncology in 2024. We comment on the evolving nature of predictive molecular events used to select patients who will most benefit clinically from treatment. We also discuss advances in the development of strategic treatment regimens for combination therapies, rational drug design of small-molecule inhibitors, and structurally informed drug repurposing.
Topics & Concepts
RepurposingPrecision oncologyDrug repositioningDrug developmentMedicineAnticancer drugDrugOncologyIntensive care medicineComputational biologyInternal medicineMedical physicsBioinformaticsPharmacologyCancerBiologyEcologyCancer Genomics and DiagnosticsProtein Degradation and InhibitorsLung Cancer Treatments and Mutations