Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage
Zhonghua Liu, Chuanping Wang, Jie Yang, Yinghua Chen, Bowen Zhou, Derek W. Abbott, Tsan Sam Xiao
Topics & Concepts
BiologyCleavage (geology)Cell biologyCaspaseCaspase 3Substrate specificityApoptosisGeneticsBiochemistryEnzymeProgrammed cell deathPaleontologyFracture (geology)Inflammasome and immune disordersErythrocyte Function and PathophysiologyToxin Mechanisms and Immunotoxins