Organophotoredox/palladium dual catalytic decarboxylative Csp<sup>3</sup>–Csp<sup>3</sup>coupling of carboxylic acids and π-electrophiles
Kaitie C. Cartwright, Jon A. Tunge
Abstract
) bonds between readily available carboxylic acids and functionally diverse carbonate electrophiles has been developed. The new process is mild, operationally simple, and has greatly improved upon the efficiency and generality of previous methodology. In addition, new insights into the reaction mechanism have been realized and provide further understanding of the harnessed reactivity.
Topics & Concepts
ElectrophileCatalysisDecarboxylationChemistryCarboxylic acidPalladiumCarbonateCombinatorial chemistryOrganic chemistryCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques