Clinical Outcomes of Treated and Untreated C. difficile PCR-Positive/Toxin-Negative Adult Hospitalized Patients: a Quasi-Experimental Noninferiority Study
Catherine A. Hogan, Matthew M. Hitchcock, Spencer Frost, Kristopher Kapphahn, Marisa Holubar, Lucy S. Tompkins, Niaz Banaei
Abstract
Clostridioides difficile infection (CDI) is routinely diagnosed by PCR, with or without toxin enzyme immunoassay testing. The role of therapy for positive PCR and negative toxin remains unclear.
Topics & Concepts
ClostridioidesToxinImmunoassayInternal medicineMedicineC difficileClostridium difficile toxin AGastroenterologyMicrobiologyClostridium difficileBiologyAntibioticsImmunologyAntibodyClostridium difficile and Clostridium perfringens researchViral gastroenteritis research and epidemiologyMicroscopic Colitis