Preferential Self-interaction of DNA Methyltransferase DNMT3A Subunits Containing the R882H Cancer Mutation Leads to Dominant Changes of Flanking Sequence Preferences
Alexandra Mack, Max Emperle, Philipp Schnee, Sabrina Adam, Jürgen Pleiss, Pavel Bashtrykov, Albert Jeltsch
Topics & Concepts
DNAProtein subunitMutationChemistryMolecular biologyGeneticsBiologyGeneEpigenetics and DNA MethylationAcute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics