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Neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy in resectable and borderline resectable pancreatic cancer (PREOPANC-2): a multicentre, open-label, phase 3 randomised trial

Quisette P. Janssen, Jacob L. van Dam, Marlies L. van Bekkum, Bert A. Bonsing, Hendrik Bos, Koop P Bosscha, Stefan A.W. Bouwense, Lieke Brouwer-Hol, A. Bruynzeel, Olivier R. Busch, Peter‐Paul L. O. Coene, Casper H.J. van Eijck, J.W.B. de Groot, Brigitte C.M. Haberkorn, Ignace H J T de Hingh, Tom M. Karsten, Geert Kazemier, Marion van der Kolk, Mike S.L. Liem, O. J. L. Loosveld, Saskia Luelmo, Misha Luyer, Leonie J. Mekenkamp, J. Sven D. Mieog, Vincent B. Nieuwenhuijs, Joost J. Nuyttens, Gijs A Patijn, Hjalmar C. van Santvoort, Martijn W.J. Stommel, Eva Versteijne, Judith de Vos‐Geelen, Roeland F. de Wilde, Babs M. Zonderhuis, Bronno van der Holt, Marjolein Y.V. Homs, Geertjan van Tienhoven, Marc G. Besselink, Johanna W. Wilmink, Bas Groot Koerkamp, Eva M M Verkolf, Esther N. Dekker, Laurens V. Beerepoot, Geert A. Cirkel, Diederik ten Oever, Mirte Mayke Streppel, Suzan Vrijaldenhoven

2025The Lancet Oncology31 citationsDOIOpen Access PDF

Topics & Concepts

FOLFIRINOXMedicineOncologyInternal medicineChemoradiotherapyPancreatic cancerNeoadjuvant therapyPhases of clinical researchRadiation therapyGemcitabineChemotherapyRandomized controlled trialClinical trialCancerFluorouracilPhase (matter)OxaliplatinRadiologySurgeryOverall survivalPancreatic and Hepatic Oncology ResearchPancreatitis Pathology and TreatmentCholangiocarcinoma and Gallbladder Cancer Studies
Neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy in resectable and borderline resectable pancreatic cancer (PREOPANC-2): a multicentre, open-label, phase 3 randomised trial | Litcius