Litcius/Paper detail

Synthesis of novel pyrazino[1,2-a]indol-1(2H)-one derivatives as potent cholinesterase inhibitors and their in vitro and in silico evaluations

Burak Kuzu, Yeliz Demir

2025Archives of Biochemistry and Biophysics15 citationsDOI

Topics & Concepts

ButyrylcholinesteraseTacrineCholinesteraseIn silicoAcetylcholinesteraseChemistryDocking (animal)PharmacologyAchéDonepezilDrug discoveryEnzymeBiochemistryStereochemistryComputational biologyBiologyMedicineDementiaNursingPathologyDiseaseGeneCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity