Encephalitozoon cuniculi Genotype III Evinces a Resistance to Albendazole Treatment in both Immunodeficient and Immunocompetent Mice
Bohumil Sak, Klára Brdíčková, Nikola Holubová, Dana Květoňová, Lenka Hlásková, Martin Kváč
Abstract
Of four genotypes of Encephalitozoon cuniculi , E. cuniculi genotype II is considered to represent a parasite that occurs in many host species in a latent asymptomatic form, whereas E. cuniculi genotype III seems to be more aggressive, and infections caused by this strain can lead to the death of even immunocompetent hosts. Although albendazole has been considered suitable for treatment of Encephalitozoon species, its failure in control of E. cuniculi genotype III infection has been reported.
Topics & Concepts
AlbendazoleEncephalitozoon cuniculiGenotypeBiologyMicrobiologyMicrosporidiaVirologyImmunocompetenceImmunologySporeImmune systemGeneticsGeneEcologyParasitic Infections and DiagnosticsParasites and Host InteractionsHelminth infection and control