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Potential therapeutic approaches for the early entry of SARS-CoV-2 by interrupting the interaction between the spike protein on SARS-CoV-2 and angiotensin-converting enzyme 2 (ACE2)

Yusen Xiang, Mengge Wang, Hongzhuan Chen, Lili Chen

2021Biochemical Pharmacology22 citationsDOIOpen Access PDF

Topics & Concepts

Angiotensin-converting enzyme 2ProteaseCoronavirusVirologyVirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Spike ProteinViral entryLipid bilayer fusionDrug discoveryCoronavirus disease 2019 (COVID-19)Antiviral drugDrug developmentBiologyPandemicEnzymeDrugComputational biologyMedicinePharmacologyBioinformaticsInfectious disease (medical specialty)DiseaseViral replicationBiochemistryPathologySARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery MethodsCOVID-19 Clinical Research Studies
Potential therapeutic approaches for the early entry of SARS-CoV-2 by interrupting the interaction between the spike protein on SARS-CoV-2 and angiotensin-converting enzyme 2 (ACE2) | Litcius