Litcius/Paper detail

Hydroperoxidations of Alkenes using Cobalt Picolinate Catalysts

Zulema Peralta-Neel, K. A. Woerpel

2021Organic Letters14 citationsDOIOpen Access PDF

Abstract

Hydroperoxides were synthesized in one step from various alkenes using Co(pic)2 as the catalyst with molecular oxygen and tetramethyldisiloxane (TMDSO). The hydration product could be obtained using a modified catalyst, Co(3-mepic)2, with molecular oxygen and phenylsilane. Formation of hydroperoxides occurred through a rapid Co–O bond metathesis of a peroxycobalt compound with isopropanol.

Topics & Concepts

ChemistryCobaltCatalysisOrganic chemistryCombinatorial chemistryPorphyrin and Phthalocyanine ChemistryOxidative Organic Chemistry ReactionsMetal-Catalyzed Oxygenation Mechanisms