Metformin coordinates with mesenchymal cells to promote VEGF-mediated angiogenesis in diabetic wound healing through Akt/mTOR activation
Fangzhou Du, Mengmeng Liu, Jingwen Wang, Lvzhong Hu, Dongao Zeng, Shaocong Zhou, Lixing Zhang, Meijia Wang, Xi Xu, Chenglong Li, Jingzhong Zhang, Shuang Yu
Topics & Concepts
AngiogenesisPI3K/AKT/mTOR pathwayWound healingMesenchymal stem cellProtein kinase BMedicineCancer researchVascular endothelial growth factorTransplantationPharmacologyImmunologyPathologyInternal medicineCell biologyBiologySignal transductionVEGF receptorsMesenchymal stem cell researchMetabolism, Diabetes, and CancerWound Healing and Treatments