Copper/DTBP-Promoted Oxyselenation of Propargylic Amines with Diselenides and CO<sub>2</sub>: Synthesis of Selenyl 2-Oxazolidinones
Jiamin Chen, Qi Lin, Linlin Zhang, Li‐Jun Li, Cong‐Ying Hou, Wei Li, Lijin Wang
Abstract
A highly efficient electrophilic oxyselenation of propargylic amines with diselenides and CO2 under atmospheric pressure promoted by copper/DTBP is reported. Various biologically important selenyl 2-oxazolidinones were produced in moderate to excellent yields. The developed method features a broad substrate scope, easy scalability, and mild reaction conditions.
Topics & Concepts
ChemistryElectrophileCopperSubstrate (aquarium)Combinatorial chemistryScope (computer science)CatalysisOrganic chemistryProgramming languageComputer scienceGeologyOceanographyCarbon dioxide utilization in catalysisOrganoselenium and organotellurium chemistrySulfur-Based Synthesis Techniques