Nano-chemical priming strategy to enhance TGF-β resistance and anti-tumor activity of natural killer cells
Seung Hee Choi, Hui Bang Cho, Jin‐Ho Choi, Hye Jin Kim, Hye Jung Jang, Seohyun Cho, Eunchong Maeng, Hail Park, Ki Seo Ryu, Keun‐Hong Park, Kyung‐Soon Park
Topics & Concepts
Tumor microenvironmentDegranulationPriming (agriculture)ChemistryInterleukin 12NanogelCancer cellNKG2DCancer researchTransforming growth factorPolyethylenimineCancer immunotherapyCytotoxicityCell biologyImmunotherapyCytotoxic T cellImmune systemImmunologyIn vitroBiologyDrug deliveryCancerTransfectionReceptorBiochemistryBotanyGerminationOrganic chemistryGeneGeneticsImmune Cell Function and InteractionCAR-T cell therapy researchImmune cells in cancer