Arsenene Nanodots with Selective Killing Effects and their Low‐Dose Combination with ß‐Elemene for Cancer Therapy (Adv. Mater. 37/2021)
Chuang LIU, Shan Sun, Qiang Feng, Gongwei Wu, Yiting Wu, Na Kong, Zhangsen Yu, Junlie Yao, Xingcai Zhang, Wei Chen, Zhongmin Tang, Yufen Xiao, Xiangang Huang, Aman Lv, Chenyang Yao, Haibo Cheng, Aiguo Wu, Tian Xie, Wei Tao
Abstract
Arsenical Drugs In article number 2102054, Aiguo Wu, Tian Xie, Wei Tao, and co-workers reveal PEGylated arsenene nanodots (AsNDs@PEG) with high monoelemental arsenic purity and negligible systemic toxicity as a new-concept arsenical drug. This AsNDs@PEG, when applied in a low-dose combination strategy with β-elemene, a plant-derived anticancer drug, achieves synergistic therapeutic outcomes.
Topics & Concepts
NanodotMaterials scienceNanotechnologyDrugPEG ratioPharmacologyMedicineFinanceEconomicsCarbon and Quantum Dots Applications