Mitochondria targeted nanoparticles to generate oxygen and responsive-release of carbon monoxide for enhanced photogas therapy of cancer
Hao Ren, Qingqing Yang, Jiahui Yong, Xue Fang, Zheng Yang, Zhangya Liu, Xing Jiang, Wenjun Miao, Xueming Li
Abstract
could accumulate at tumor sites and with laser irradiation, tumor growth was significantly inhibited due to the enhanced PDT, PTT, and CO gas therapy. This study provides a strategy with oxygen generating and thermal-responsive CO release to combine phototherapy and CO gas therapy for cancer treatment.
Topics & Concepts
Carbon monoxideMitochondrionCancer therapyOxygenChemistryNanoparticleReactive oxygen speciesBiophysicsCancerNanotechnologyBiochemistryMaterials scienceMedicineBiologyCatalysisOrganic chemistryInternal medicineNanoplatforms for cancer theranosticsHeme Oxygenase-1 and Carbon MonoxidePhotodynamic Therapy Research Studies