Ipilimumab with or without nivolumab in PD-1 or PD-L1 blockade refractory metastatic melanoma: a randomized phase 2 trial
Ari M. Vanderwalde, Shay Bellasea, Kari Kendra, Nikhil I. Khushalani, Katie M. Campbell, Philip O. Scumpia, Lawrence F. Kuklinski, Frances A. Collichio, Jeffrey A. Sosman, Alexandra P. Ikeguchi, Adrienne I. Victor, Thach‐Giao Truong, Bartosz Chmielowski, David C. Portnoy, Yuanbin Chen, Kim Margolin, Charles Bane, Constantin A Dasanu, Douglas B. Johnson, Zeynep Eroglu, Sunandana Chandra, Egmidio Medina, Cynthia R. Gonzalez, Ignacio Baselga-Carretero, Agustin Vega-Crespo, Ivan Perez Garcilazo, Elad Sharon, Siwen Hu‐Lieskovan, Sapna P. Patel, Kenneth F. Grossmann, James Moon, Michael C. Wu, Antoni Ribas
Topics & Concepts
IpilimumabNivolumabMedicineClinical endpointBlockadeInternal medicineOncologyHazard ratioAdverse effectMelanomaProgression-free survivalTremelimumabPhases of clinical researchConfidence intervalClinical trialCancerImmunotherapyChemotherapyCancer researchReceptorCancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmunotherapy and Immune Responses