Short-Term Outcomes of Laparoscopic Proximal Gastrectomy With Double-Tract Reconstruction Versus Laparoscopic Total Gastrectomy for Upper Early Gastric Cancer: A KLASS 05 Randomized Clinical Trial
Sun-Hwi Hwang, Do Joong Park, Hyung‐Ho Kim, Woo Jin Hyung, Hoon Hur, Han‐Kwang Yang, Hyuk-Joon Lee, Hyoung‐Il Kim, Seong-Ho Kong, Young‐Woo Kim, Han Hong Lee, Beom Su Kim, Young-Kyu Park, Young‐Joon Lee, Sang-Hoon Ahn, In‐Seob Lee, Yun‐Suhk Suh, Ji-Ho Park, Soyeon Ahn, Sang‐Uk Han
Abstract
PURPOSE: Laparoscopic proximal gastrectomy with double-tract reconstruction (LPG-DTR) is a function-preserving procedure performed for treating upper early gastric cancer (EGC). However, few studies have compared the outcomes of LPG-DTR with those of laparoscopic total gastrectomy (LTG). This study aimed at comparing the short-term outcomes of LPG-DTR between LTG and upper EGC. MATERIALS AND METHODS: For upper-third EGC, a multicenter, prospective, randomized trial was performed to compare those who underwent LPG-DTR with those who underwent LTG. Short-term outcomes, including clinicopathologic results, morbidity, mortality, and postoperative courses, were evaluated using a full analysis set based on the intention-to-treat principle and the per-protocol set. RESULTS: 0.749). Laboratory findings on postoperative day 5 were not significantly different between the groups. CONCLUSIONS: The short-term outcomes of LPG-DTR for upper EGC were comparable to those of LTG. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02892643.