Silymarin alleviates docetaxel-induced central and peripheral neurotoxicity by reducing oxidative stress, inflammation and apoptosis in rats
Ahmet Yardım, Sefa Küçükler, Selçuk Özdemir, Selim Çomaklı, Cüneyt Çağlayan, Fatih Mehmet Kandemır, Hamit Çelik
Topics & Concepts
NeurotoxicityOxidative stressSuperoxide dismutaseNeuroprotectionPharmacologyGlutathione peroxidasep38 mitogen-activated protein kinasesSciatic nerveGlial fibrillary acidic proteinGlutathioneEndocrinologyBiologyInternal medicineProtein kinase AMedicineImmunologyKinaseBiochemistryToxicityEnzymeImmunohistochemistrySilymarin and Mushroom PoisoningCancer Treatment and PharmacologyIon channel regulation and function