Effect of charge status on the ion transport and antimicrobial activity of synthetic channels
Pengyang Xin, Lingyu Zhao, Linlin Mao, Linqi Xu, Shuaimin Hou, Huiyuan Kong, Haodong Fang, Haofeng Zhu, Tao Jiang, Chang-Po Chen
Abstract
The charge status of channels formed by pillararene–gramicidin hybrid molecules has a significant impact on their trans-membrane transport properties, membrane-association abilities and antimicrobial activities.
Topics & Concepts
AntimicrobialMembraneGramicidinCharge (physics)ChemistryIon channelMoleculeBiophysicsIonIon transporterChemical physicsNanotechnologyCombinatorial chemistryMaterials scienceBiochemistryOrganic chemistryBiologyPhysicsQuantum mechanicsReceptorMolecular Sensors and Ion DetectionLuminescence and Fluorescent MaterialsSupramolecular Chemistry and Complexes