Metal‐Coordinated Adsorption of Nanoparticles to Macrophages for Targeted Cancer Therapy (Adv. Funct. Mater. 19/2023)
Mao‐Hua Zhu, Xin‐Di Zhu, Mei Long, Xing Lai, Yihang Yuan, Yanhu Huang, Lele Zhang, Yuhao Gao, Jiangpei Shi, Qin Lu, Peng Sun, Jonathan F. Lovell, Hongzhuan Chen, Chao Fang
Abstract
Macrophages In article number 2214842, Chao Fang and co-workers develop a macrophage-drug delivery system (Mφ-DDS) with doxorubicin (DOX)-loaded polymeric nanoparticles (NPs) on cell surface, named as [email protected]φ. At the tumor site, the photothermal effect can disintegrate the cell-nanoparticle composites and liberate DOX-NP for improved cellular uptake and chemotherapy.
Topics & Concepts
Photothermal therapyMaterials scienceNanoparticleDoxorubicinDrug deliveryNanotechnologyAdsorptionMetalCancer therapyMacrophageCancer cellCancer treatmentCancer researchBiophysicsChemotherapyCancerMedicineChemistryBiochemistryOrganic chemistryMetallurgyBiologySurgeryIn vitroInternal medicineNanoplatforms for cancer theranosticsAdvanced Nanomaterials in Catalysis