Litcius/Paper detail

Hydrogermylation of Alkenes via Organophotoredox-Initiated HAT Catalysis

Adele E. Queen, Aymane Selmani, Franziska Schoenebeck

2021Organic Letters61 citationsDOI

Abstract

This Letter discloses the straightforward hydrogermylation of olefins under visible-light organophotoredox-initiated HAT catalysis conditions to yield primary and secondary alkyl germanes at room temperature. The protocol is operationally simple, metal-free, and tolerant of various functional groups. The synthesized alkyl germanes proved to be highly robust toward acidic, basic, or oxidizing conditions and chemical transformations of Csp2–GeEt3 or Csp2–BPin functionalities in their presence.

Topics & Concepts

ChemistryOxidizing agentAlkylCatalysisYield (engineering)Combinatorial chemistryMetalOrganic chemistryMaterials scienceMetallurgyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions