Mukaiyama aldol reaction: an effective asymmetric approach to access chiral natural products and their derivatives/analogues
Aqsa Mushtaq, Ameer Fawad Zahoor
Abstract
This review highlights the significance of the Mukaiyama aldol reaction towards the asymmetric synthesis of a wide range of biologically active natural products reported recently (since 2020).
Topics & Concepts
Aldol reactionEnantioselective synthesisChemistrySilyl enol etherKetoneAldehydeLewis acids and basesAdductEnolOrganic chemistryLewis acid catalysisSilylationCatalysisAsymmetric Synthesis and CatalysisMarine Sponges and Natural ProductsAlkaloids: synthesis and pharmacology