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Design, synthesis and bioactivity of novel naphthalimide-benzotriazole conjugates against A549 cells via targeting BCL2 G-quadruplex and inducing autophagy

Xiao Wang, Mi Zhang, Xuqiong Xiong, Hao Yang, Panpan Wang, Koutian Zhang, Annoor Awadasseid, Suresh Narva, Yanling Wu, Wen Zhang

2022Life Sciences13 citationsDOI

Topics & Concepts

ChemistryFlow cytometryA549 cellBlotApoptosisIntracellularMolecular biologyCell biologyBiochemistryBiologyGeneDNA and Nucleic Acid ChemistryMetal complexes synthesis and propertiesCancer therapeutics and mechanisms
Design, synthesis and bioactivity of novel naphthalimide-benzotriazole conjugates against A549 cells via targeting BCL2 G-quadruplex and inducing autophagy | Litcius