Development and validation of an LC-MS/MS method for the quantification of flavonoid glucuronides (wogonoside, baicalin, and apigenin-glucuronide) in the bile and blood samples: Application to a portal vein infusion study
Yifan Tu, Lei Zhou, Li Li, Lu Wang, Song Gao, Ming Hu
Topics & Concepts
ChromatographyChemistryBaicalinGlucuronideGlucuronidationProtein precipitationTaurocholic acidFormic acidMass spectrometryTandem mass spectrometryWogoninSolid phase extractionHigh-performance liquid chromatographyBile acidMetaboliteBiochemistryEnzymePathologyAlternative medicineMedicineTraditional Chinese medicineScutellaria baicalensisMicrosomeFlavonoids in Medical ResearchTraditional Chinese Medicine AnalysisPhytochemistry and Biological Activities