A HER2 target antibody drug conjugate combined with anti-PD-(L)1 treatment eliminates hHER2+ tumors in hPD-1 transgenic mouse model and contributes immune memory formation
Lei Huang, Ruiqin Wang, Kun Xie, Jingming Zhang, Fei Tao, Chenyu Pi, Feng Yan, Hua Gu, Jianmin Fang
Topics & Concepts
Cancer researchImmune systemImmunotherapyCancerBreast cancerMedicineImmune checkpointAntibodyAntibody-drug conjugateCombination therapyImmunologyPharmacologyMonoclonal antibodyInternal medicineCancer Immunotherapy and BiomarkersHER2/EGFR in Cancer ResearchCancer Cells and Metastasis