APOE ε4 and late-life cognition: mediation by structural brain imaging markers
Yuan Ma, Gautam Sajeev, Tyler J. VanderWeele, Anand Viswanathan, Sigurður Sigurdsson, Guðný Eiríksdóttir, Thor Aspelund, Rebecca A. Betensky, Francine Grodstein, Albert Hofman, Vilmundur Guðnason, Lenore J. Launer, Deborah Blacker
Topics & Concepts
MedicineWhite matterApolipoprotein EMagnetic resonance imagingHyperintensityCognitive declineCognitionLesionPopulationBrain sizePathologyNeuropsychologyDementiaInternal medicineNeuroscienceDiseasePsychologyRadiologyPsychiatryEnvironmental healthAlzheimer's disease research and treatmentsDementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments