Multi-cancer early detection (MCED) tests: prioritizing equity from bench to bedside
Sarah J Miller, Jamilia Sly, Christian Rolfo, Philip C. Mack, Augusto Villanueva, Melissa Mazor, Ellerie Weber, Jenny J. Lin, Cardinale B. Smith, Emanuela Taioli
Abstract
Multi-cancer early detection (MCED) tests are blood-based tests designed to screen for signals of multiple cancers. There is growing interest and investment in examining the potential benefits and applications of MCED tests. If MCED tests are shown to have clinical utility, it is important to ensure that all people-regardless of their demographic or socioeconomic background-equitably benefit from these tests. Unfortunately, with health care innovation, such considerations are often ignored until after inequities emerge. We urge for-profit companies, scientists, clinicians, payers, and government agencies to prioritize equity now-when MCEDs are still being developed and researched. In an effort to avoid creating and exacerbating cancer inequities, we propose 9 equity considerations for MCEDs.