Are drug holidays a safe option in treatment of osteoporosis? — Insights from an in silico mechanistic PK–PD model of denosumab treatment of postmenopausal osteoporosis
Javier Martínez‐Reina, José Luis Calvo‐Gallego, Peter Pivonka
2020Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials26 citationsDOIOpen Access PDF
Topics & Concepts
DenosumabMedicineDiscontinuationDrug holidayOsteoporosisBone mineralClinical trialBone remodelingBone resorptionDrugInternal medicineOncologyPhysical therapyPharmacologyFamily medicineHuman immunodeficiency virus (HIV)Bone health and osteoporosis researchBone and Joint DiseasesBone Metabolism and Diseases