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Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Seung Pil Yun, Tae‐In Kam, Nikhil Panicker, Sang‐Min Kim, Yumin Oh, Jong Sung Park, Seung‐Hwan Kwon, Yong Joo Park, Senthilkumar S. Karuppagounder, Hyejin Park, Sangjune Kim, Nayeon Oh, Nayoung Alice Kim, Saebom Lee, Saurav Brahmachari, Xiaobo Mao, Jun Hee Lee, Manoj Kumar, Daniel An, Sung-Ung Kang, Yunjong Lee, Kang Choon Lee, Dong Hee Na, Donghoon Kim, Sang Hun Lee, Viktor Roschke, Shane A. Liddelow, Zoltán Mari, Ben A. Barres, Valina L. Dawson, Seulki Lee, Ted M. Dawson, Han Seok Ko, Seulki Lee, Ted M. Dawson, Han Seok Ko

2018Nature Medicine1,140 citationsDOI

Topics & Concepts

NeuroprotectionMicrogliaAgonistAstrocyteNeuroscienceDopaminergicParkinson's diseaseMPTPNeurodegenerationMedicineSubstantia nigraPharmacologyReceptorBiologyCentral nervous systemDopamineInflammationInternal medicineDiseaseNeuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease | Litcius