Photocatalytic Multicomponent 1,<i>n</i>-Carboimination with Alkyl Iodides and <i>O</i>-Benzoyl Oxime through EnT and XAT Processes
Xue-Ling Luo, Miao-Sha Huang, Shanshan Li, Shanshan Li, Yu‐Shi Jiang, Li-Ning Chen, Shu‐Hui Li, Shu‐Hui Li, Peng‐Ju Xia
Abstract
-benzoyl oxime to efficiently introduce alkyl and iminyl groups via energy transfer and halogen-atom transfer processes. We performed three-component 1,2-carboimination of olefins and four-component 1,4-carboimination across olefins and alkynes, resulting in the synthesis of over 60 nitrogen-containing molecules. Moreover, this transformation enables the synthesis of molecules with sensitive groups that were previously difficult to achieve.
Topics & Concepts
AlkylChemistryOximeHalogenMoleculeNitrogen atomCombinatorial chemistryComponent (thermodynamics)Organic chemistryThermodynamicsPhysicsCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsRadical Photochemical Reactions