Antigen-specific T cell activation through targeted delivery of in-situ generated antigen and calcium ionophore to enhance antitumor immunotherapy
Xue Chen, Hongling Ouyang, Yunxiao Zhang, Conglin Chen, Simin Nan, Ximing Pu, Tao Gong, Zhirong Zhang, Renhe Liu, Yao Fu
Topics & Concepts
AntigenImmune systemT cellChemistryImmunotherapyAntigen-presenting cellImmunologyCell biologyT-cell receptorCancer researchMedicineBiologyImmunotherapy and Immune ResponsesCAR-T cell therapy researchNanoplatforms for cancer theranostics