Litcius/Paper detail

Menopausal shift on women’s health and microbial niches

Maria R. Nieto, Maria J. Rus, Victoria Areal‐Quecuty, Daniel María Lubián López, Áurea Simón‐Soro

2025npj Women s Health29 citationsDOIOpen Access PDF

Abstract

Menopause marks a key milestone in women’s aging, triggering hormonal, histological, and microbiome changes. This review explores how hormonal shifts during menopause alter the microbiome’s composition, affecting oral, intestinal, and urogenital communities, potentially leading to disease. The microbial metabolism of sex hormones highlights the bidirectional relationship between hormones and the microbiome. Understanding this interplay is crucial for developing personalized interventions to restore microbial balance and improve women’s health during menopause.

Topics & Concepts

Ecological nicheNicheEnvironmental healthGeographyMedicineBiologyEcologyHabitatReproductive tract infections researchGut microbiota and healthDermatology and Skin Diseases