Droplet-based functional CRISPR screening of cell–cell interactions by SPEAC-seq
Camilo Faust Akl, Mathias Linnerbauer, Zhaorong Li, Hong‐Gyun Lee, Iain C. Clark, Michael A. Wheeler, Francisco J. Quintana
Topics & Concepts
CRISPRComputational biologyCas9BiologyCell typeCell sortingCellMicrofluidicsHigh-throughput screeningGenomeEmbryonic stem cellGenome editingCell biologyBioinformaticsGeneticsNanotechnologyGeneMaterials scienceNeuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomicsCRISPR and Genetic Engineering