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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory

Alessio Lanna, Bruno Vaz, Clara D’Ambra, Salvatore Valvo, Claudia Vuotto, Valerio Chiurchiù, Oliver Devine, Massimo Sanchez, Giovanna Borsellino, Arne N. Akbar, Marco De Bardi, Derek W. Gilroy, Michael L. Dustin, Brendan Blumer, Michael Karin

2022Nature Cell Biology158 citationsDOIOpen Access PDF

Topics & Concepts

TelomereCell biologyTelomeraseShelterinSenescenceBiologyGeneticsDNATranscription factorGeneDNA-binding proteinNeutrophil, Myeloperoxidase and Oxidative MechanismsTelomeres, Telomerase, and SenescenceCytomegalovirus and herpesvirus research
An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory | Litcius