New synthetic chitosan Schiff bases bearing pyranoquinolinone or benzonaphthyridine and their silver nanoparticles derivatives with potential activity as antioxidant and molecular docking study for EGFR inhibitors
Shrouk M. Hassan, Jehan M. Morsy, Hany M. Hassanin, Elham S. Othman, M. Mostafa
Abstract
Two chitosan-based Schiff bases, CS1 and CS2 were synthesized, and they were grafted onto silver nanoparticles, creating CS1/Ag and CS2/Ag structures. They were assessed as antioxidant and EGFR inhibitors.
Topics & Concepts
Docking (animal)ChemistryAntioxidantCombinatorial chemistrySchiff baseChitosanStereochemistryOrganic chemistryMedicineNursingSynthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Characterization of Heterocyclic Compounds