Beyond chloroquine: Cationic amphiphilic drugs as endosomal escape enhancers for nucleic acid therapeutics
Aliona Debisschop, Bram Bogaert, Cristina Muntean, Stefaan C. De Smedt, Koen Raemdonck
Topics & Concepts
Nucleic acidEndosomeAmphiphileCationic polymerizationEnhancerChloroquineChemistryCombinatorial chemistryBiochemistryComputational biologyPharmacologyBiologyMalariaOrganic chemistryCellImmunologyCopolymerGeneGene expressionPolymerRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesCytomegalovirus and herpesvirus research