The proliferation effects of fluoxetine and amitriptyline on human breast cancer cells and the underlying molecular mechanisms
Bingli Lei, Lanbing Xu, Xiaolan Zhang, Wei Peng, Qianqian Tang, Chenglian Feng
Topics & Concepts
GPERProtein kinase BMAPK/ERK pathwayFluoxetinePI3K/AKT/mTOR pathwayCell growthCancer researchSKBR3PharmacologyChemistryEstrogen receptorDownregulation and upregulationPhosphorylationCell biologySignal transductionCancerCancer cellBiologyMedicineInternal medicineBreast cancerReceptorBiochemistryHuman breastSerotoninGeneEstrogen and related hormone effectsCancer, Stress, Anesthesia, and Immune ResponseReceptor Mechanisms and Signaling