Pathogenesis of autoimmune hepatitis
Junhua Fan, Geng-Feng Liu, Xiaodan Lv, Ruizhi Zeng, Lingling Zhan, Xiaoping Lv
Abstract
Autoimmune hepatitis (AIH) is a chronic progressive liver disease whose etiology and pathogenesis are not yet clear. It is currently believed that the occurrence of AIH is closely related to genetic susceptibility and immune abnormalities, and other factors such as environment, viral infection and drugs that may cause immune dysfunction. This article reviews the pathogenesis of AIH and describes the latest research results in the past 5 years.
Topics & Concepts
PathogenesisMedicineAutoimmune hepatitisImmunologyEtiologyGenetic predispositionImmune systemDiseaseHepatitisImmune DysfunctionAutoimmune diseaseViral hepatitisPathologyAntibodyLiver Diseases and ImmunityLiver Disease Diagnosis and TreatmentHepatitis Viruses Studies and Epidemiology