hTERT-molecular targeted therapy of ovarian cancer cells via folate-functionalized PLGA nanoparticles co-loaded with MNPs/siRNA/wortmannin
Somayyeh Ghareghomi, Shahin Ahmadian, Nosratollah Zarghami, Salar Hemmati
Topics & Concepts
Ovarian cancerTelomerase reverse transcriptaseWortmanninCytotoxicityPLGATelomeraseTargeted therapyChemistryDrug deliveryTargeted drug deliverySmall interfering RNACancer researchMTT assayIn vitroPI3K/AKT/mTOR pathwayPharmacologyBiophysicsTransfectionMaterials scienceNanotechnologyCancerMedicineBiochemistryBiologyApoptosisInternal medicineGeneRNA Interference and Gene DeliveryNanoparticle-Based Drug DeliveryAdvanced biosensing and bioanalysis techniques