Discovery of novel thiophene [2,3-D] pyrimidine–thiazole derivative as promising MNK inhibitor to treat breast cancer
Peng Zhu, You Yang, Jianqiang Qian, Jun Han, Dairui Kong, Bo Sun, Jian Zhang, Jingtao Wei, Qulian Guo, Sihui Nian, Lixiang Zhou, Guodong Wang, Shaohua Hou
Topics & Concepts
ChemistryThiazolePyrimidineThiopheneDerivative (finance)Breast cancerCombinatorial chemistryCancerPharmacologyCancer researchStereochemistryOrganic chemistryInternal medicineBiologyFinancial economicsMedicineEconomicsSynthesis and biological activityCancer Mechanisms and TherapyQuinazolinone synthesis and applications