Bioinformatic tools for epitranscriptomics
Y‐h. Taguchi
Abstract
The epitranscriptome, defined as RNA modifications that do not involve alterations in the nucleotide sequence, is a popular topic in the genomic sciences. Because we need massive computational techniques to identify epitranscriptomes within individual transcripts, many tools have been developed to infer epitranscriptomic sites as well as to process datasets using high-throughput sequencing. In this review, we summarize recent developments in epitranscriptome spatial detection and data analysis and discuss their progression.
Topics & Concepts
Computational biologyBiologySequence (biology)Computer scienceData scienceGeneticsRNA modifications and cancerCancer-related molecular mechanisms researchRNA and protein synthesis mechanisms