MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression
Ao Wang, Fangtian Bu, Juanjuan Li, Yafei Zhang, Pengcheng Jia, Hongmei You, Sha Wu, Yuanyuan Wu, Sai Zhu, Cheng Zhi Huang, Jun Li
Topics & Concepts
Hepatic stellate cellPTENHepatic fibrosisDownregulation and upregulationPI3K/AKT/mTOR pathwayCancer researchGene knockdownFibrosisExtracellular matrixProtein kinase BCell biologymicroRNAChemistryBiologySignal transductionEndocrinologyInternal medicineApoptosisMedicineBiochemistryGeneLiver physiology and pathologyOrgan Transplantation Techniques and OutcomesCholangiocarcinoma and Gallbladder Cancer Studies