The C-Type Lectin Receptor Dectin-2 Is a Receptor for Aspergillus fumigatus Galactomannan
Jennifer L. Reedy, Arianne J. Crossen, Paige E. Negoro, Hannah Brown, Rebecca Ward, Diego A. Vargas-Blanco, Kyle D. Timmer, Christopher M. Reardon, Kyle J. Basham, Michael K. Mansour, Marcel Wüthrich, Thierry Fontaine, Jean‐Paul Latgé, Jatin M. Vyas
Abstract
Aspergillus fumigatus is a fungal pathogen that causes serious and often fatal disease in humans. The surface of Aspergillus is composed of complex sugar molecules.
Topics & Concepts
GalactomannanAspergillus fumigatusC-type lectinMicrobiologyBiologyLectinAspergillusImmune systemAspergillosisMannanImmunologyBiochemistryPolysaccharideAntifungal resistance and susceptibilityFungal Infections and StudiesPleural and Pulmonary Diseases