Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract
Joan C. Smith, Erin L. Sausville, Vishruth Girish, Monet Lou Yuan, Anand Vasudevan, Kristen M. John, Jason M. Sheltzer
Topics & Concepts
BiologyAngiotensin-converting enzyme 2Downregulation and upregulationRespiratory tractReceptorImmunologyLungInflammationPopulationInterferonRespiratory systemVirologyCoronavirus disease 2019 (COVID-19)GeneInternal medicineMedicineGeneticsAnatomyInfectious disease (medical specialty)Environmental healthDiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSingle-cell and spatial transcriptomics